On setting a condition under which Sell Orders may not be submitted in respect of ordinary shares of ordinary shares of Avidity Biosciences, Inc. (RNA)

Herewith ITS Ltd. informs that starting from 17.02.2026 Sell Orders may not be submitted in respect of ordinary shares of Avidity Biosciences, Inc. (ISIN US05370A1088, RNA), hereinafter referred to as the Qualified Investments, provided that the following condition is met:

SO_N > CM.AccB_N + CM_Cl.N – CM_Ob.N – USO_N, where:

• SO_N - number of securities indicated in the Sell Order submitted in respect of the Qualified Investments.
• AccB_N - number of securities recorded in the Trading and Clearing Account specified in the Sell Order in respect of the Qualified Investments.
• CM_N - number of securities which constitute Clearing and Trading Member’s claims in the Qualified Investments that will be recorded in the Trading and Clearing Account specified in the Sell Order at the time of Sell Order submission.
• CM_N - number of securities which constitute Clearing and Trading Member’s obligations that will be recorded in the Trading and Clearing Account specified in the Sell Order at the time of Sell Order submission.
• USO_N - number of securities indicated in the unfulfilled Trading Member’s Sell Orders, which contain reference to the Trading and Clearing Account that coincides with Trading and Clearing Account referred to in the submitted Sell Order.

The present condition shall not apply to Category A Trading Members, provided that Sell Orders contain reference to short codes and/or Trading and Clearing Accounts specified in agreements on maintaining prices, demand and offer and (or) turnover.