On additional information on corporate action affecting ordinary shares of Cara Therapeutics, Inc. (CARA)

On April 14, 2025, Cara Therapeutics, Inc. (CARA) announced that the 1-for-3 reverse stock split will become effective after the market close on April 15, 2025. On April 16, 2025 common shares of Cara Therapeutics, Inc. are expected to begin trading on a reverse stock split-adjusted basis under the new name “Tvardi Therapeutics, Inc.”, new ISIN code US1407553072 and new ticker «TVRD». For more details, please, refer to the company’s website.

ITS Ltd. will publish separate notices on the procedures undertaken by ITS Ltd. to process this corporate action outlining how trading in these qualified investments will be carried out.